Endress+hauser U 500 Proline Promass Coriolis flowmeter
- Accuracy: ±0.5% mass flow
- Applications: Biopharmaceutical, Life Sciences
- Verification: Heartbeat Technology integrated
- Compliance: cGMP, ASME BPE
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Description
Endress+Hauser Promass U 500: Biotech Single-Use Specialist
Ideal Flowmeter for Biopharmaceutical Applications
The Endress+Hauser Promass U 500 is engineered as the ideal single-use flowmeter, specifically designed for the biopharmaceutical sector within the life sciences industry. It directly addresses the industry’s evolving trends towards single-use devices and continuous manufacturing processes, moving away from traditional multi-use systems and batch production. This innovative flowmeter supports enhanced reliability, high accuracy, and crucial industry compliance, including cGMP standards, making it a perfect fit for modern biotech manufacturing.
Pioneering Single-Use Flow Measurement Technology
This advanced flowmeter represents a significant leap in single-use technology. The system comprises a disposable sensor component, available in four convenient line sizes, and a permanently installed, versatile base unit that seamlessly fits all disposable sensor variants. This clever design ensures maximum flexibility and reduces inventory complexity, a key benefit in dynamic bioprocessing environments.
Automated Verification Simplifies Commissioning
A standout feature of the Promass U 500 is its integrated Heartbeat Technology. Upon installation, the sensor automatically recognizes the flow range and verifies the validity of the factory calibration. This intelligent self-commissioning capability significantly simplifies setup and entirely eliminates the need for any on-site calibration, saving valuable time and resources.
Enhancing Process Efficiency with Multivariable Measurement
The Promass U 500 provides enhanced process insights through its multivariable measurement capabilities, accurately capturing mass, density, and temperature simultaneously. This allows for a reduction in the number of required process measuring points, thereby simplifying system architecture and lowering overall costs. The transmitter further boosts efficiency with its freely configurable I/O functionality and modern communication protocols.
Designed for Upstream and Downstream Processes
Specifically, the Promass U 500 is exceptionally well-suited for both upstream and downstream applications within the monoclonal antibodies (mAb) production process. Its ability to provide accurate and reliable measurements in these critical stages ensures the quality and consistency of biopharmaceutical products, supporting the complex workflows involved in developing life-saving therapies.
cGMP Compliance and Traceability Assured
Adhering to the highest industry standards, the Promass U 500 is designed in accordance with the latest cGMP guidelines. The disposable components are made from traceable materials (1.4435 stainless steel and polycarbonate), ensuring full compliance and providing the necessary documentation for regulatory requirements. This commitment to compliance underscores its suitability for sensitive biopharmaceutical manufacturing.
Your Premier Global Source: Discover tpt24 for Promass U 500
For biopharmaceutical applications demanding accuracy, reliability, and compliance in single-use processes, the Endress+Hauser Promass U 500 is the leading solution. tpt24 is the premier global online store for this exceptional flowmeter. We provide an absolute guarantee of product authenticity and superior quality with every purchase. tpt24 ensures your Promass U 500 meets the highest performance standards, and our worldwide delivery network guarantees secure and efficient procurement to any country, establishing us as your essential global partner.
Specifications
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Measuring principle
Coriolis
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Product headline
Single-use specialist for Biotech applications, with a remote version with up to 4 I/Os.
Modern fieldbus communication protocols (2-wire).
Highest measurement performance for liquids in single-use processes for the Life Sciences Industry. -
Sensor features
One sensor fits all DN – single variant with 4 disposable line sizes provides highest turndown ratio . One-hand mounting of disposable – easy
commissioning due to intuitive clamping mechanism. Mounting angle – self drainabillity or air bubble escape.
Disposable made of 1.4435 (316L) and polycarbonate. Fully traceable cGMP compliance. One sensor fits four line sizes: ¹⁄₈ to 1″. -
Transmitter features
Full access to process and diagnostic information –
numerous, freely combinable I/Os and Ethernet. Reduced complexity and variety – freely configurable I/O functionality. Integrated verification – Heartbeat Technology.
Remote version with up to 4 I/Os. Backlit display with touch control and WLAN access. Standard cable between sensor and transmitter. -
Nominal diameter range
¹⁄₈” to 1″
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Wetted materials
Measuring tubes: Stainless steel 1.4435, 316L
Hose connection nipple: Makrolon Rx 1805 polycarbonate -
Measured variables
Mass, density, temperature
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Max. measurement error
Mass flow (liquid): ±0.5%
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Measuring range
0 to 75 kg/h (0 to 165,3 lb/min)
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Max. process pressure
6 bar (87 psi)
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Medium temperature range
3 to 60°C (37.4 to 140°F)
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Ambient temperature range
5 to 40°C (41 to 104°F)
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Transmitter housing material
Aluminum, AlSi10Mg, coated
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Degree of protection
Transmitter: IP66/67, Type 4X enclosure
Sensor: IP54 -
Display/Operation
4-line backlit display with touch control (operation from outside)
Configuration via local display and operating tools possible -
Outputs
“4 outputs:
4-20 mA HART (active/passive)
4-20 mA WirelessHART
4-20 mA (active/passive)
Pulse/frequency/switch output (active/passive)
Double pulse output (active/passive)
Relay output” -
Inputs
Status input
4-20 mA input -
Digital communication
Modbus RS485, PROFINET over Ethernet-APL
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Power supply
AC 100 to 230 V / DC 24 V (non-hazardous area)
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Product safety
CE, C-tick, EAC marking
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Functional safety
Functional safety according to IEC 61508, applicable in safety-relevant applications in accordance with IEC 61511
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Hygienic approvals and certificates
cGMP compliance, ASME BPE, BPOG, FDA











